PHYTOCHEMICAL SCREENING, GAS CHROMATOGRAPHY-MASS SPECTROMETRY AND FOURIER TRANSFORM INFRARED EVALUATIONS OF ETHANOLIC EXTRACT OF Allium sativum

Authors

  • Umar Tanko Mamza Department of Pure and Applied Chemistry, Faculty of Physical Sciences, University of Maiduguri, Borno State, Nigeria
  • Marshal Wilson Department of Pure and Applied Chemistry, Faculty of Physical Sciences, University of Maiduguri, Borno State, Nigeria
  • James Yakubu Department of Pure and Applied Chemistry, Faculty of Physical Sciences, University of Maiduguri, Borno State, Nigeria
  • Irfan Zahir Khan Department of Pure and Applied Chemistry, Faculty of Physical Sciences, University of Maiduguri, Borno State, Nigeria
  • Bukar Wakil Department of Chemistry, Faculty of Science, Federal University, Gashua, Yobe State, Nigeria.
  • Elijah Joshua Maiva Department of Biochemistry, Faculty of Life Sciences, University of Maiduguri, Maiduguri, Borno State, Nigeria

Keywords:

Gas Chromatography Mass Spectrometry; Fourier Transform Infrared Spectroscopy; Allium sativum; Phytochemicals

Abstract

This study aimed to identify the bioactive compounds present in the ethanolic extract of Allium sativum by Gas Chromatography-Mass Spectrometry (GC-MS) and FTIR techniques. The presence of phytochemicals in the plant were also carried out using standard procedures. The phytochemical analysis revealed the presence of flavonoid, cardenolides, cardiac glycosides, Saponins, Carbohydrates and Terpenoids. The results of GC-MS analysis revealed the total of twenty-three (23) compounds, amongst which some have been reported to be good therapeutic agents this include, cycloheaxanone, 3,5-dimethoxy cis (antimicrobial), 5 hydroxymethyl furfural (antioxidant), 1-hexacosene (anti-inflammatory) and Magnesium, bis(4, N,N dimethylaminobutyl (antibacterial). The FTIR results revealed different functional groups present in the compound present in the extract, this includes alcohol, carboxylic acids, ester, alkene among others. The results study concluded that the plant has important phytochemicals of great therapeutic importance especially, antimicrobial, anti-inflammatory, antioxidant.

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2024-06-22

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